Scientists Find New Early Warning Sign That Could Indicate Alzheimer’s Disease

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Every 3 minutes, someone on earth grows dementia, most commonly in the form of Alzheimer’s disease. Having an ever-aging world population, that figure is just going to become greater over the forthcoming years. That’therefore scientists at the University of Birmingham, UK, have been working to discover strategies to diagnose and forecast this condition that is progressive.

They discovered that fighting to read simple words could be an early indication that a person is at risk of developing Alzheimer&rsquo disorder. Although it’s early days for its study, they believe the study can be used to create a low-cost and non-invasive method to forecast the onset of Alzheimer’s disease as early as possible.

“A prominent feature of Alzheimer’s is a progressive decrease in speech, however, the capability to process language in the period between the appearance of first symptoms of Alzheimer’s to its full development has scarcely previously been researched,” Dr Ali Mazaheri, of the University of Birmingham, stated in a statement.

“We wanted to inquire whether there were anomalies in brain activity during speech processing in MCI patients that could offer insight in their likelihood of developing Alzheimer’s. We concentrated on language working, since it’s a crucial feature of cognition and particularly affected throughout the progressive stages of Alzheimer’s.”

As explained in a new study published in Neuroimage Clinical, the investigators gathered 25 comparatively healthy seniors with mild cognitive impairment (MCI), a condition seen in 20 percent of individuals over 65, which frequently develops into Alzheimer’s. The experiment involved them completing a language comprehension task while hooked up to an electroencephalogram (EEG), a method that measures and records the electrical activity of the brain.   With their findings, they were able to predict which patients would go on to develop Alzheimer’s disease within the next three decades.

“Crucially, what we found in our research is that this brain response is aberrant in individuals who will go on in the future to develop Alzheimer’s disease, however intact in patients who remained stable,” added co-author Dr Katrien Segaert.  

“Our findings were unexpected as speech is generally affected by Alzheimer’s disease in much later stages of the onset of the disease. ”

Today the authors   hope their work will lead to additional research in this particular location.    

“It is possible that this breakdown of their brain system connected with speech comprehension in MCI patients could be a crucial biomarker used to identify patients likely to develop Alzheimer’s disease.   We hope to now examine the validity of this biomarker in big population of patients in the UK to see whether it is a specific predictor of Alzheimer’s disease, or a general markers for dementia involving the temporal lobe,” Segaert explained.

Read more: http://www.iflscience.com

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